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Cancer tumours eradicated by genetically modified immune cells



Illustration of modified spiky viruses entering and altering a T-cell as part of the gene-editing process

Science Photo Library/Alamy

Human tumours in mice have been eradicated by human immune cells that were genetically engineered to boost their anticancer activity.

So far, engineered immune cells have proved ineffective against solid tumours in human trials, but these cells could prove more potent.

The tests in the mice, which were also engineered so that their immune systems were made of human cells, are “as close as you can get to the human system”, says Stephen Hatfield

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